Here are results reported by Ditto, Spano, and coworkers. |
Atrial Fibrillation, or AFib, is the most common cardiac
arrhythmia requiring treatment. It occurs in over 5% of the population over 65 and
increases the risk of stroke and death. |
These experiments were performed on 25 patients at Emory University. |
(1) For each patient, AFib was induced and an unstable fixed point determined from the
return map of the interbeat intervals. |
(2) A learning phase determined how the fixed point changed as the stimulus was varied. |
(3) Then the method of contol was applied to keep the interbeat interval near this fixed point. |
This method worked in 3/4 of the patients, though in about half of these, the control
was more short-lived. |
Pictured on the right are histograms of the distribution of
the return map before (upper graph) and after (lower graph) control was implemented. |
The strong central spike in the middle of the lower graph demonstrates the effectiveness
of the control method. Note the change of vertical scale between the two graphs. |